Asbestos Exposure and Asbestosis

Asbestos exposure, asbestosis, and asbestos-attributable lung cancer.

The study was designed to test the hypothesis that the risk of lung cancer from asbestos exposure is confined to persons with radiographic evidence of pulmonary fibrosis. Occupational and smoking histories were obtained from 271 patients with a confirmed diagnosis of primary lung cancer and 678 referents (279 with other respiratory disease and 399 with cardiac disease). Histories were reviewed ...

Airways obstruction from asbestos exposure and asbestosis revisited.

obstruction (reduced FEF25-75 and FEF75-85) as shown in 8,720 asbestos-exposed workers who at various times during this evolution show irregular opacities as seen in the chest x-ray films.1 Thus, the disease's functional signs precede the radiographic manifestations. This was confirmed pathologically as fibrosis was found far more often on tissue sections when lung was examined from asbestos wo...

Asbestos lung burden and asbestosis after occupational and environmental exposure in an asbestos cement manufacturing area: a necropsy study.

OBJECTIVE The largest Italian asbestos cement factory had been active in Casale Monferrato until 1986: in previous studies a substantial increase in the incidence of pleural mesothelioma was found among residents without occupational exposure to asbestos. To estimate exposure to asbestos in the population, this study evaluated the presence of histological asbestosis and the lung burden of asbes...

Inflammation and asbestosis: characterization and maintenance of alveolitis following acute asbestos exposure.

Asbestosis, pleural plaques and diffuse pleural thickening: three distinct benign responses to asbestos exposure.

The aim of this study was to investigate by computed tomography (CT) whether asbestosis, diffuse pleural thickening and/or pleural plaques are statistically associated. We also tried to find criteria to differentiate between diffuse and circumscribed pleural thickening. From 231 exposed workers, only those subjects whose radiograph showed neither bilateral calcified pleural plaques nor small pu...